Diseases treatable by transplants

 

A bone marrow or cord blood transplant may be the best treatment option or the only source for a cure & treatment for patients with leukemia, lymphoma, sickle cell anemia, and many other diseases. As the science of transplant continues to advance, new diseases are being treated with transplants.

 

Leukaemia’s and lymphomas, including:

 

Acute myelogenous leukemia (AML) —The most common type of acute leukemia with nearly 15,0000 new cases found across the globe each year. AML can affect people of any age but is most common in adults.

 

Acute lymphoblastic leukemia (ALL) —There are about 6,0000 new cases of Across the globe each year. It can affect people of any age but is the most common type of leukemia in children under 15.

 

Chronic lymphocytic leukemia (CLL) — Primarily an adult disease, CLL is very rare in children and young adults. About 15,0000 people are diagnosed each year in the world.

 

Chronic myelogenous leukemia (CML) — A relatively common form of leukemia, it affects more than 200,000 people cases each year. Most cases of CML appear in adults.

 

Juvenile myelomonocytic leukemia

 

Hodgkin lymphoma

 

Non-Hodgkin lymphoma (NHL) — Each year about 69,0000 people are diagnosed with NHL in the World. Most of these people are older than 60.

 

Bone marrow diseases and other diseases when bone marrow fails to work, including:

 

Severe aplastic anemiaA rare disease with 6000-9000 people diagnosed each year. The disease appears more often in eastern Asian countries. It can affect people of any age but is most common in young adults.

 

Fanconi anemia

 

Paroxysmal nocturnal hemoglobinuria (PNH)

 

Pure red cell aplasia

 

Amegakaryocytosis/congenital thrombocytopenia

 

Inherited immune system disorders, including:

 

Severe combined immunodeficiency (SCID, all types) SCID is a group of inherited immune system disorders that are present at birth. They can become life-threatening within the first year of life if left untreated. In the world, about 1 in 1000,000 approximately babies are born with SCID.

 

Wiskott-Aldrich syndrome (WAS) — WAS is an inherited immune system disorder that is present at birth. It affects mostly boys. In the globe, about 1 in 1000,000 boys are born with it.

Hemoglobinopathies (diseases with poorly functioning red blood cells), including:

 

Beta thalassemia major

 

Sickle cell disease (SCD) — Sickle cell disease is an inherited disease of the red blood cells. In the world, it affects about 700,000-1000,000 people approximately and is most common among African Americans and Hispanics

 

Inherited metabolic disorders, including:

 

Krabbe disease (GLD) — GLD is very rare. Only about 400 children are diagnosed in the world each year. Most often it appears in the first months of life (early-onset). There is also another form of the disease that doesn’t show until later in childhood or even into teenage years (late-onset).

 

 Hurler syndrome (MPS-IH) This occurs in about 1 of every 100,000 babies born. If not treated, children born with this disease usually die by 5 to 10 years of age.

 

Adrenoleukodystrophy (ALD) — Both boys and girls can be born with ALD, but boys are more likely to have symptoms. One out of 3 boys born with ALD has the most severe form of it, cerebral X-linked ALD. The form is rare, affecting about 1 in 20,000 individuals worldwide.

 

Metachromatic leukodystrophy (MLD) — MLD appears most often in babies and young toddlers, but it also occurs in older children and adults. MLD is rare. It occurs in about 1 in 40,000 to 160,000 individuals worldwide.

 

Myelodysplastic syndromes and myeloproliferative disorders. MDS is a group of diseases that affect the bone marrow and blood. About 190,000 approximately people are diagnosed with MDS in the world each year.

 

Multiple myeloma and other plasma cell disorders

 

Familial erythrophagocytic lymphohistiocytosis and other histiocytic disorders

 

Certain other malignancies or cancers

 

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